TABLE 2.
Comparison of tuberculosis indicators pre- (2001–2010) and post-introduction (2011–2019) of GeneXpert in three high tuberculosis burden countries in Africa.
| Variable | Democratic Republic of the Congo |
Nigeria |
South Africa |
|||
|---|---|---|---|---|---|---|
| Difference | p | Difference | p | Difference | p | |
| New confirmed pulmonary tuberculosis cases | 23 358 | 0.0002 | 22 335 | 0.0011 | 2125 | 0.7413 |
| Estimated number of cases | 67 667 | < 0.0001 | 92 222 | < 0.0001 | −42 889 | 0.5081 |
| Estimated incidence/100k | −3.1 | 0.0067 | - | - | −217 | 0.1066 |
| New extrapulmonary cases | 4994 | 0.0007 | 2134 | 0.0006 | −9551 | 0.1544 |
| Laboratory confirmed RR/MDR-TB† | - | - | - | |||
| Laboratory confirmed MDR-TB† | - | - | - | |||
| Tuberculosis case notification numbers | 41 726 | 0.0001 | 32 348 | 0.0001 | 6084 | 0.8818 |
| Case notification rate/100k | 7.8 | 0.2634 | 7.6 | 0.0680 | −57.1 | 0.4901 |
| Tuberculosis case detection rate % | 2.7 | 0.2305 | 3.3 | 0.0743 | 6.2 | 0.0108 |
| Estimated tuberculosis/HIV % | −4.5 | 0.0190 | −3.9 | 0.1604 | −6.6 | < 0.0001 |
| Estimated mortality/100k | −8.2 | 0.0264 | −6.0 | 0.0001 | −254 | < 0.0001 |
| TSR new cases % | 9.0 | 0.0201 | 8.4 | 0.0001 | 9.6 | 0.0017 |
Source: World Health Organization (WHO). Global Tuberculosis Programme. In Global TB report [homepage on the Internet]. 2021 [cited 2021 Jun 26]. Available from: https://www.who.int/tb/country/data/download/en/
MDR-TB, multidrug-resistant tuberculosis; TSR, treatment success rate; RR, rifampicin resistant tuberculosis
†
, No data to enable comparison.