TABLE 4.
Sensitivity analysis of specific contributions of herbs.
| Tier | Composition | No. of RCTs | Effect estimates (EE) | 95% CI of EE | I2 statistics (%) |
|---|---|---|---|---|---|
| 1 | Dandelion | 5 | 1.47 | 1.17, 1.83 | 0.00 |
| 1 | Paris Polyphylla | 3 | 1.47 | 1.07, 2.02 | 10.95 |
| 1 | Red paeony | 4 | 1.46 | 1.13, 1.88 | 0.00 |
| 1 | Chinese Angelica | 14 | 1.44 | 1.27, 1.64 | 9.33 |
| 1 | Astragalus | 13 | 1.43 | 1.25, 1.64 | 0.00 |
| 1 | Scutellaria Barbata | 8 | 1.41 | 1.18, 1.69 | 28.11 |
| 1 | Villous Amomum | 7 | 1.40 | 1.13, 1.73 | 33.15 |
| 1 | Smilax | 6 | 1.40 | 1.17, 1.67 | 8.17 |
| 1 | White Paeony | 10 | 1.39 | 1.20, 1.61 | 14.62 |
| 1 | Ginseng | 6 | 1.39 | 1.17, 1.65 | 0.00 |
| 1 | Codonopsis | 18 | 1.38 | 1.23, 1.55 | 5.92 |
| 1 | Acruginous Turmeric | 15 | 1.36 | 1.20, 1.54 | 16.12 |
| 1 | Poria | 21 | 1.35 | 1.23,1.49 | 0.00 |
| 1 | Largehead Atractylodes | 26 | 1.34 | 1.23,1.47 | 0.00 |
| 1 | Gekko | 6 | 1.33 | 1.10, 1.60 | 14.72 |
| 1 | Tangerine Peel | 17 | 1.32 | 1.18, 1.47 | 6.29 |
| 1 | Hedyotis Diffusa | 12 | 1.32 | 1.16, 1.50 | 3.56 |
| 1 | Membrane of Chickens Gizzard | 7 | 1.32 | 1.11, 1.57 | 0.00 |
| 1 | Salviae | 4 | 1.32 | 1.04, 1.67 | 0.00 |
| 1 | Liquorice | 23 | 1.30 | 1.18, 1.42 | 0.00 |
| 1 | Pinellia | 20 | 1.28 | 1.17, 1.41 | 0.00 |
| 2 | Codonopsis + Villous Amomum | 4 | 1.70 | 1.34, 2.16 | 0.00 |
| 2 | Ginseng + Cornus | 2 | 1.56 | 1.16, 2.10 | 0.00 |
| 2 | Acruginous Turmeric + Astragalus | 7 | 1.55 | 1.28, 1.88 | 0.00 |
| 2 | Chinese Angelica + Astragalus | 7 | 1.55 | 1.28, 1.89 | 0.00 |
| 2 | Chinese Angelica + Smilax | 5 | 1.55 | 1.27, 1.88 | 0.00 |
| 2 | Acruginous Turmeric + Cassia Twig | 4 | 1.54 | 1.23, 1.91 | 0.00 |
| 2 | Scutellaria Barbata + Membrane of Chickens Gizzard | 3 | 1.53 | 1.18, 1.98 | 0.00 |
| 2 | Chinese Angelica + Myrrh | 3 | 1.52 | 1.15, 2.00 | 0.00 |
| 2 | Largehead Atractylodes + Wolfberry | 4 | 1.51 | 1.22, 1.89 | 0.00 |
| 2 | Astragalus + Villous Amomum | 4 | 1.50 | 1.11, 2.03 | 25.93 |
| 2 | Codonopsis + Astragalus | 8 | 1.47 | 1.23, 1.76 | 0.00 |
| 2 | Liquorice + Bupleurum | 5 | 1.46 | 1.19, 1.79 | 0.00 |
| 2 | Codonopsis + Chinese Angelica | 8 | 1.46 | 1.20, 1.77 | 27.05 |
| 2 | Codonopsis + Aucklandia | 6 | 1.46 | 1.20, 1.77 | 0.00 |
| 2 | Largehead Atractylodes + Scutellaria Barbata | 7 | 1.44 | 1.19, 1.74 | 27.24 |
| 2 | Largehead Atractylodes + White Paeony | 9 | 1.41 | 1.21, 1.63 | 12.42 |
| 2 | Largehead Atractylodes + Ginseng | 3 | 1.41 | 1.21, 1.78 | 0.00 |
| 2 | Largehead Atractylodes + Membrane of Chickens Gizzard | 5 | 1.40 | 1.14, 1.73 | 0.00 |
| 2 | Acruginous Turmeric + Hedyotis Diffusa | 8 | 1.40 | 1.16, 1.70 | 21.43 |
| 2 | Membrane of Chickens Gizzard + Gekko | 4 | 1.40 | 1.12, 1.76 | 0.00 |
| 2 | Largehead Atractylodes + Yam | 9 | 1.38 | 1.18, 1.62 | 13.56 |
| 2 | Liquorice + Poria | 17 | 1.36 | 1.22, 1.52 | 0.00 |
| 2 | Pinellia + Gekko | 5 | 1.35 | 1.10, 1.65 | 14.01 |
| 2 | Pinellia + Magnolia Bark | 4 | 1.30 | 1.04, 1.64 | 0.00 |
| 2 | Pinellia + Dried Ginger | 4 | 1.29 | 1.03, 1.61 | 1.47 |
| 3 | Chinese Angelica + Astragalus + Villous Amomum | 3 | 1.73 | 1.26, 2.36 | 0.00 |
| 3 | Largehead Atractylodes + Wolfberry + Psoralea | 2 | 1.65 | 1.24, 2.19 | 0.00 |
| 3 | Codonopsis + Chinese Angelica + Astragalus | 6 | 1.60 | 1.30, 1.97 | 0.00 |
| 3 | Liquorice + Codonopsis + Bupleurum | 3 | 1.57 | 1.14, 2.15 | 0.00 |
| 3 | Pinellia + White Paeony + Dried Ginger | 2 | 1.56 | 1.10, 2.21 | 0.00 |
| 3 | Codonopsis + Acruginous Turmeric + Astragalus | 5 | 1.53 | 1.22, 1.91 | 0.00 |
| 3 | Largehead Atractylodes + Astragalus + White Paeony | 5 | 1.52 | 1.26, 1.84 | 0.00 |
| 3 | Largehead Atractylodes + Poria + Aucklandia | 5 | 1.51 | 1.22, 1.86 | 0.00 |
| 3 | Largehead Atractylodes + Acruginous Turmeric + Membrane of Chickens Gizzard | 4 | 1.51 | 1.19, 1.91 | 0.00 |
| 3 | Acruginous Turmeric + Chinese Angelica + Astragalus | 5 | 1.51 | 1.21, 1.89 | 0.00 |
| 3 | Acruginous Turmeric + Hedyotis Diffusa + Red paeony | 3 | 1.51 | 1.14, 2.01 | 0.00 |
| 3 | Scutellaria Barbata + Membrane of Chickens Gizzard + Gekko | 2 | 1.51 | 1.11, 2.04 | 0.00 |
| 3 | Largehead Atractylodes + Pinellia + Scutellaria Barbata | 5 | 1.50 | 1.18, 1.92 | 39.55 |
| 3 | Largehead Atractylodes + Astragalus + Villous Amomum | 2 | 1.50 | 1.04, 2.16 | 0.00 |
| 3 | Largehead Atractylodes + Pinellia + Dandelion | 4 | 1.49 | 1.17, 1.91 | 0.00 |
| 3 | Largehead Atractylodes + Acruginous Turmeric + Astragalus | 6 | 1.47 | 1.20, 1.80 | 0.00 |
| 3 | Liquorice + Codonopsis + Aucklandia | 5 | 1.47 | 1.15, 1.86 | 0.00 |
| 3 | Largehead Atractylodes + Acruginous Turmeric + Scutellaria Barbata | 4 | 1.46 | 1.12, 1.89 | 39.92 |
| 3 | Largehead Atractylodes + Chinese Angelica + Astragalus | 6 | 1.46 | 1.19, 1.80 | 0.00 |
| 3 | Largehead Atractylodes + Astragalus + Coxi Seed | 6 | 1.46 | 1.21, 1.78 | 0.00 |
| 3 | Largehead Atractylodes + Pinellia + Astragalus | 5 | 1.44 | 1.17, 1.77 | 0.00 |
| 3 | Largehead Atractylodes + Tangerine Peel + White Paeony | 6 | 1.44 | 1.19, 1.74 | 27.78 |
| 3 | Acruginous Turmeric + Hedyotis Diffusa + Cassia Twig | 3 | 1.44 | 1.12, 1.84 | 0.00 |
| 3 | Largehead Atractylodes + Pinellia + White Paeony | 6 | 1.43 | 1.15, 1.77 | 29.02 |
| 3 | Codonopsis + White Paeony + Aucklandia | 3 | 1.41 | 1.09, 1.82 | 0.00 |
| 3 | Liquorice + White Paeony + Bupleurum | 4 | 1.40 | 1.11, 1.76 | 0.00 |
| 3 | Largehead Atractylodes + Poria + Suberect Spatholobus | 3 | 1.39 | 1.05, 1.83 | 0.00 |
| 3 | Pinellia + Tangerine Peel + Barley Sprout | 5 | 1.39 | 1.10, 1.75 | 4.55 |
| 3 | Pinellia + Gekko + Magnolia Bark | 3 | 1.39 | 1.06, 1.81 | 0.00 |
| 3 | Largehead Atractylodes + Tangerine Peel + Yam | 6 | 1.38 | 1.13, 1.69 | 22.74 |
| 3 | Largehead Atractylodes + Liquorice + Poria | 16 | 1.37 | 1.22, 1.53 | 0.00 |
| 3 | Largehead Atractylodes + Pinellia + Membrane of Chickens Gizzard | 4 | 1.36 | 1.08, 1.72 | 0.00 |
| 4 | Codonopsis + Chinese Angelica + Astragalus + Villous Amomum | 2 | 1.95 | 1.36, 2.78 | 0.00 |
| 4 | Largehead Atractylodes + Pinellia + Tangerine Peel + Dandelion | 2 | 1.76 | 1.24, 2.52 | 0.00 |
| 4 | Acruginous Turmeric + Chinese Angelica + Astragalus + Villous Amomum | 2 | 1.75 | 1.01, 3.03 | 34.11 |
| 4 | Liquorice + Pinellia + Tangerine Peel + Paris Polyphylla | 2 | 1.74 | 1.18, 2.56 | 0.00 |
| 4 | Largehead Atractylodes + Tangerine Peel + Astragalus + Yam | 4 | 1.63 | 1.30, 2.05 | 0.00 |
| 4 | Codonopsis + Acruginous Turmeric + Chinese Angelica + Astragalus | 4 | 1.57 | 1.24, 1.99 | 0.00 |
| 4 | Largehead Atractylodes + Liquorice + Poria + Aucklandia | 4 | 1.55 | 1.19, 2.02 | 0.00 |
| 4 | Largehead Atractylodes + Tangerine Peel + Acruginous Turmeric + Astragalus | 4 | 1.54 | 1.23, 1.93 | 0.00 |
| 4 | Largehead Atractylodes + Poria + Chinese Angelica + Astragalus | 5 | 1.53 | 1.23, 1.91 | 0.00 |
| 4 | Largehead Atractylodes + Astragalus + Wolfberry + Cuscuta | 3 | 1.53 | 1.12, 2.08 | 0.00 |
| 4 | Acruginous Turmeric + Chinese Angelica + Sparganii + Smilax | 4 | 1.53 | 1.24, 1.89 | 0.00 |
| 4 | Largehead Atractylodes + Liquorice + Poria + Villous Amomum | 4 | 1.52 | 1.19, 1.93 | 0.00 |
| 4 | Largehead Atractylodes + Liquorice + Poria + Bupleurum | 4 | 1.51 | 1.22, 1.89 | 0.00 |
| 4 | Largehead Atractylodes + Poria + Codonopsis + Aucklandia | 5 | 1.51 | 1.22, 1.86 | 0.00 |
| 4 | Largehead Atractylodes + Pinellia + Tangerine Peel + Barley Sprout | 4 | 1.50 | 1.15, 1.97 | 3.91 |
| 4 | Largehead Atractylodes + Codonopsis + Chinese Angelica + Astragalus | 5 | 1.50 | 1.21, 1.87 | 0.00 |
| 4 | Largehead Atractylodes + Liquorice + Chinese Angelica + Astragalus | 5 | 1.48 | 1.14, 1.02 | 0.00 |
| 4 | Largehead Atractylodes + Pinellia + Tangerine Peel + Astragalus | 4 | 1.47 | 1.19, 1.83 | 0.00 |
| 4 | Liquorice + Pinellia + Tangerine Peel + Ginseng | 2 | 1.47 | 1.12, 1.93 | 0.00 |
| 4 | Largehead Atractylodes + Poria + Tangerine Peel + Astragalus | 6 | 1.45 | 1.21, 1.73 | 0.00 |
| 4 | Largehead Atractylodes + Poria + Codonopsis + Astragalus | 6 | 1.44 | 1.18, 1.75 | 0.00 |
| 4 | Liquorice + Pinellia + Codonopsis + Aucklandia | 3 | 1.42 | 1.08, 1.85 | 0.00 |
| 4 | Liquorice + Pinellia + White Paeony + Bupleurum | 3 | 1.42 | 1.08, 1.88 | 0.00 |
| 4 | Largehead Atractylodes + Poria + Codonopsis + White Paeony | 5 | 1.40 | 1.13, 1.73 | 23.16 |
| 4 | Largehead Atractylodes + Acruginous Turmeric + Coxi Seed + Yam | 4 | 1.39 | 1.12, 1.72 | 30.94 |
| 4 | Largehead Atractylodes + Liquorice + Poria + Aurantii Fructus | 3 | 1.38 | 1.05, 1.81 | 0.00 |
| 4 | Largehead Atractylodes + Acruginous Turmeric + Membrane of Chickens Gizzard + Crataegi | 3 | 1.38 | 1.05, 1.82 | 0.00 |
| 5 | Largehead Atractylodes + Pinellia + Acruginous Turmeric + Astragalus + White Paeony | 3 | 1.67 | 1.23, 2.27 | 0.00 |
| 5 | Largehead Atractylodes + Acruginous Turmeric + Astragalus + Wolfberry + Cuscuta | 2 | 1.66 | 1.15, 2.41 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Chinese Angelica + Astragalus | 4 | 1.59 | 1.19, 2.13 | 0.00 |
| 5 | Acruginous Turmeric + Chinese Angelica + Hedyotis Diffusa + Sparganii + Smilax | 3 | 1.59 | 1.22, 2.08 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Villous Amomum | 3 | 1.58 | 1.22, 2.05 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Tangerine Peel + Bupleurum | 3 | 1.58 | 1.22, 2.05 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Aucklandia | 4 | 1.55 | 1.19, 2.02 | 0.00 |
| 5 | Largehead Atractylodes + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus | 5 | 1.50 | 1.21, 1.87 | 0.00 |
| 5 | Largehead Atractylodes + Poria + Codonopsis + Tangerine Peel + Aucklandia | 3 | 1.49 | 1.12, 1.97 | 0.00 |
| 5 | Largehead Atractylodes + Poria + Codonopsis + Acruginous Turmeric + Astragalus | 3 | 1.48 | 1.14, 1.93 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + White Paeony + Bupleurum | 3 | 1.46 | 1.13, 1.88 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Coptis | 2 | 1.45 | 1.08, 1.94 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Tangerine Peel + Astragalus | 5 | 1.45 | 1.17, 1.78 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + White Paeony | 4 | 1.44 | 1.07, 1.93 | 33.23 |
| 5 | Largehead Atractylodes + Poria + Codonopsis + Hedyotis Diffusa + Suberect Spatholobus | 2 | 1.43 | 1.04, 1.97 | 0.00 |
| 5 | Largehead Atractylodes + Liquorice + Poria + Hedyotis Diffusa + Scutellaria Barbata | 5 | 1.42 | 1.14, 1.77 | 26.53 |
| 6 | Largehead Atractylodes + Pinellia + Tangerine Peel + White Paeony + Scutellaria Barbata + Barley Sprout | 2 | 2.04 | 1.37, 3.05 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Tangerine Peel + Bupleurum | 2 | 1.84 | 1.24, 2.72 | 0.00 |
| 6 | Largehead Atractylodes + Acruginous Turmeric + Coxi Seed + Yam + Scutellaria Barbata + Membrane of Chickens Gizzard | 2 | 1.76 | 1.27, 2.45 | 0.00 |
| 6 | Largehead Atractylodes + Pinellia + Coxi Seed + Inula + Haematitum | 2 | 1.68 | 1.25, 2.25 | 0.00 |
| 6 | Largehead Atractylodes + Poria + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus | 4 | 1.59 | 1.25, 2.01 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus | 4 | 1.55 | 1.16, 2.06 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Codonopsis + Villous Amomum | 2 | 1.53 | 1.11, 2.10 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + White Paeony + Bupleurum + Aurantii Fructus | 2 | 1.52 | 1.05, 2.20 | 0.00 |
| 6 | Largehead Atractylodes + Poria + Chinese Angelica + Coxi Seed + Yam + Smilax | 3 | 1.52 | 1.18, 1.95 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Codonopsis + Aucklandia | 2 | 1.51 | 1.11, 2.06 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Tangerine Peel + Astragalus + Bupleurum | 2 | 1.51 | 1.15, 1.98 | 0.00 |
| 6 | Largehead Atractylodes + Poria + Codonopsis + Chinese Angelica + Yam + Aucklandia | 3 | 1.51 | 1.13, 2.00 | 0.00 |
| 6 | Largehead Atractylodes + Tangerine Peel + Acruginous Turmeric + Barley Sprout + Cassia Twig + Dried Ginger | 2 | 1.49 | 1.10, 2.03 | 3.12 |
| 6 | Largehead Atractylodes + Pinellia + Acruginous Turmeric + Membrane of Chickens Gizzard + Gekko + Dandelion | 3 | 1.48 | 1.13, 1.95 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Tangerine Peel + Astragalus | 4 | 1.47 | 1.13, 1.91 | 0.00 |
| 6 | Largehead Atractylodes + Poria + Acruginous Turmeric + Chinese Angelica + Astragalus + White Paeony | 3 | 1.47 | 1.13, 1.91 | 0.00 |
| 6 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Tangerine Peel + Coptis | 2 | 1.45 | 1.08, 1.94 | 0.00 |
| 7 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus | 3 | 1.75 | 1.25, 2.38 | 0.00 |
| 7 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Tangerine Peel + White Paeony + Bupleurum | 2 | 1.53 | 1.11, 2.11 | 0.00 |
| 7 | Largehead Atractylodes + Liquorice + Poria + Chinese Angelica + Coxi Seed + Yam + Smilax | 2 | 1.61 | 1.12, 2.34 | 0.00 |
| 7 | Largehead Atractylodes + Pinellia + Tangerine Peel + Acruginous Turmeric + Astragalus + White Paeony + Scutellaria Barbata | 2 | 1.86 | 1.31, 2.62 | 0.00 |
| 8 | Largehead Atractylodes + Liquorice + Poria + Pinellia + Tangerine Peel + Astragalus + White Paeony + Alisma Orientale | 2 | 1.51 | 1.13, 2.02 | 0.00 |
| 8 | Largehead Atractylodes + Poria + Codonopsis + Tangerine Peel + Acruginous Turmeric + Chinese Angelica + Astragalus + White Paeony | 2 | 1.53 | 1.15, 2.04 | 0.00 |
| 8 | Largehead Atractylodes + Poria + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus + Yam + Aucklandia | 2 | 1.47 | 1.06, 2.04 | 0.00 |
| 8 | Largehead Atractylodes + Poria + Acruginous Turmeric + Chinese Angelica + Coxi Seed + Yam + Sparganii + Smilax | 2 | 1.50 | 1.13, 1.97 | 0.00 |
| 9 | Largehead Atractylodes + Liquorice + Poria + Codonopsis + Tangerine Peel + Chinese Angelica + Astragalus + Yam + Lotus Seed | 2 | 1.70 | 1.12, 2.56 | 0.00 |
| 9 | Acruginous Turmeric + Chinese Angelica + Hedyotis Diffusa + Sparganii + Smilax + Red paeony + Cassia Twig + Myrrh + Frankincense | 2 | 1.59 | 1.15, 2.18 | 0.00 |
| 10 | Largehead Atractylodes + Poria + Codonopsis + Chinese Angelica + Coxi Seed + White Paeony + Yam + Aucklandia + Smilax + Hedyotis Chrysotricha | 2 | 1.49 | 1.11, 2.00 | 0.00 |