Figure 5.

Endothelial cell-specific loss of VCAM1 is protective against inflammation during liver fibrosis. Eight-week-old Vcam1^Δend mice and Vcam1^fl/fl mice were treated with either olive oil or CCl4 intraperitoneally (1μL/g body weight), twice a week for 4 weeks. Liver inflammation was assessed by (A) Cd68 and Ccr2 mRNA expression, (B) H&E staining and (C) F4/80 immunostaining. Scale bar: 50μm, n=3-6. ** indicate statistical significance with p < 0.01. Statistically non-significant results were labeled as ns.