Table 3.
Univariate and multivariate analysis for postoperative complications
|
Variables
|
Univariate analysis
|
P
value
|
Multivariate analysis
|
P value |
|
OR (95%CI)
|
OR (95%CI)
|
|||
| Age | 1.00 (0.93-1.08) | 0.864 | ||
| Sex | 0.85 (0.50-1.46) | 0.562 | ||
| ASA | ||||
| 1 | NA | NA | ||
| 2 | 0.51 (0.28-0.93) | 0.027 | ||
| 3 | Ref. | 1 | ||
| 4 | 9.53 (1.26-72.1) | 0.029 | ||
| BMI | 0.92 (0.85-1.01) | 0.072 | ||
| CCI | 0.82 (0.43-1.60 | 0.611 | ||
| Prior upper abdomen surgery | 0.79 (0.36-1.72) | 0.559 | ||
| Leucocytes | 1.00 (1.00-1.00) | 0.009 | ||
| Platelets | 1.00 (1.00-1.00) | 0.013 | 1.00 (1.00-1.00) | 0.0008 |
| Bilirubin | 1.23 (0.97-1.57) | 0.081 | ||
| C-reactive protein | 1.00 (0.99-1.00) | 0.195 | ||
| Antiplatelet | 1.33 (0.77-2.31) | 0.311 | ||
| Anticoagulant therapy | 1.922 (0.96-3.85) | 0.065 | ||
| Acute cholecystitis Tokyo grade | ||||
| Mild | 1.55 (0.67-3.35) | 0.324 | ||
| Moderate | 2.19 (1.11-4.32) | 0.023 | ||
| Severe | 4.54 (2.00-10.3) | 0.0003 | ||
| BIliary colic | 3.43 (1.70-6.93) | 0.0006 | ||
| Biliary pancreatitis | 1.24 (0.51-3.04) | 0.635 | ||
| Gallbladder cancer | 1.95 (0.22-17.1) | 0.543 | ||
| Choleperitoneum | 1.61 (0.58-4.45) | 0.36 | ||
| Cholangitis | 12.0 (1.59-89.7) | 0.019 | 12.7 (1.61-100.1) | 0.016 |
| Preoperative ERCP | 0.38 (0.16-0.91) | 0.03 | ||
| Admission-surgery interval | 1.04 (0.95-1.14) | 0.326 | ||
| Laparoscopy | 0.28 (0.11-0.69) | 0.005 | 0.10 (0.02-0.46) | 0.003 |
| Conversion to open surgery | 1.81 (0.37-1.42) | 0.354 | ||
| Choledocholithotomy | 1.07 (0.33-3.46) | 0.914 | ||
| Intraoperative cholangiography | 2.12 (1.23-3.64) | 0.007 | 2.99 (1.43-6.24) | 0.003 |
| Intraoperative ERCP | 1.47 (0.57-3.78) | 0.423 | ||
| Transcystic biliary decompression | 2.57 (0.73-8.95) | 0.138 | ||
| Afternoon night procedure | 2.12 (1.21-3.74) | 0.009 |
ASA: American Society of Anesthesiologists; BMI: Body mass index; ERCP: Endoscopic retrograde cholangio-pancreatography; CCI: Charlson comorbidity index; NA: Not available.