Table 4.
Univariate and multivariate analysis for postoperative complications with Clavien-Dindo grade > 2
| Variables |
Univariate analysis
|
P
value
|
Multivariate analysis
|
P value |
|
OR (95%CI)
|
OR (95%CI)
|
|||
| Age | 1.08 (0.98-1.18) | 0.122 | ||
| Sex | 0.64 (0.30-1.38) | 0.255 | ||
| ASA | ||||
| 1 | NA | |||
| 2 | 0.14 (0.02-1-12) | 0.064 | ||
| 3 | Ref. | 1 | ||
| 4 | 6.14 (2.48-15.3) | 0.001 | 12.6 (4.27-37.3) | < 0.0001 |
| BMI | 1.12 (1.00-1.26) | 0.05 | ||
| CCI | 1.19 (0.87-4.21) | 0.237 | ||
| Prior upper abdomen surgery | 1.92 (0.72-5.12) | 0.193 | ||
| Leucocytes | 1.00 (1.00-1.01) | 0.021 | ||
| Platelets | 1.00 (1.00-1.00) | 0.545 | ||
| Bilirubin | 1.37 (0.44-4.28) | 0.014 | 1.41 (1.33-1.75) | 0.002 |
| C-reactive protein | 1.00 (0.99-1.01) | 0.252 | ||
| Antiplatelet | 0.96 (0.44-2.08) | 0.916 | ||
| Anticoagulant therapy | 2.03 (0.91-4.53) | 0.083 | ||
| Acute cholecystitis Tokyo grade | ||||
| Mild | 3.33 (0.71-15.7) | 0.128 | ||
| Moderate | 3.38 (0.86-13.2) | 0.08 | ||
| Severe | 8.02 (2.21-29.0) | 0.001 | ||
| Biliary colic | 0.79 (0.33-1.87) | 0.599 | ||
| Biliary pancreatitis | 0.26 (0.03-1.98) | 0.194 | ||
| Choleperitoneum | 2.89 (1.05-7.95) | 0.039 | ||
| Cholangitis | 1.37 (0.44-4.28) | 0.579 | ||
| Preoperative ERCP | 0.74 (0.16-3.33) | 0.696 | ||
| Admission-surgery interval | 1.05 (0.99-1.11) | 0.115 | ||
| Laparoscopy | 0.18 (0.08-0.40) | < 0.001 | ||
| Conversion to open surgery | 1.81 (0.75-4.35) | 0.185 | ||
| Choledocholithotomy | 4.58 (1.45-14.5) | 0.009 | 10.2 (2.04-51.1) | 0.005 |
| Transcystic biliary decompression | 5.81 (2.20-15.4) | 0.0004 | ||
| Intraoperative cholangiography | 0.86 (0.40-1.86) | 0.706 | ||
| Intraoperative ERCP | 1.38 (0.44-4.28) | 0.579 | ||
| Afternoon night procedure | 1.82 (0.84-3.91) | 0.126 |
ASA: American Society of Anesthesiologists; BMI: Body mass index; ERCP: Endoscopic retrograde cholangio-pancreatography; CCI: Charlson comorbidity index; NA: Not available.