Table 3.

Effects of peritraumatic distress, perceived stress and depression on NR3C1 gene CpG sites methylation among pregnant women.

NR3C1 gene CpG site	Beta	SE	p	p#	Adjusted R2
Peritraumatic distress
CpG 1	−0.01	0.01	0.36	0.63	−0.01
CpG 2	−0.02	0.01	0.09	0.54	0.07
CpG 3	−0.02	0.01	0.12	0.54	0.05
CpG 4	−0.01	0.01	0.42	0.63	−0.01
CpG 5	0.001	0.01	0.91	0.94	−0.04
CpG 6	0.001	0.01	0.94	0.94	−0.04
CpG 7	0.02	0.01	0.18	0.54	0.03
CpG 8	0.01	0.01	0.73	0.94	−0.03
CpG 9	0.01	0.01	0.35	0.63	−0.003
Perceived stress
CpG 1	0.02	0.02	0.28	0.92	0.01
CpG 2	0.003	0.01	0.78	0.92	−0.03
CpG 3	−0.01	0.01	0.67	0.92	−0.03
CpG 4	0.002	0.01	0.89	0.92	−0.03
CpG 5	0.01	0.01	0.41	0.92	−0.01
CpG 6	0.01	0.01	0.72	0.92	−0.03
CpG 7	0.01	0.02	0.36	0.92	−0.01
CpG 8	0.03	0.01	0.06	0.50	0.09
CpG 9	−0.002	0.02	0.92	0.92	−0.04
Depression
CpG 1	0.02	0.02	0.22	0.25	0.02
CpG 2	0.03	0.02	0.07	0.16	0.08
CpG 3	0.03	0.02	0.13	0.19	0.05
CpG 4	0.02	0.02	0.17	0.22	0.04
CpG 5	0.02	0.01	0.11	0.19	0.03
CpG 6	0.03	0.01	0.03	0.12	0.13
CpG 7	−0.003	0.02	0.87	0.87	−0.03
CpG 8	0.05	0.02	0.003	0.03	0.21
CpG 9	0.04	0.02	0.04	0.12	0.13

The regression model was controlled for age, city, and residence.

^# Multiple testing was adjusted using the false discovery rate (FDR) method.

Bold values indicate that CpG8 was found to be significantly associated with depression.