Table 4.
Diagnostic performance of the studied miRNAs
|
Cut off
|
Sensitivity
|
Specificity
|
PPV
|
NPV
|
Accuracy
|
AUC
|
95%CI
|
P
value
|
miRNA-326 | > 1.165 | 0.971 | 0.52 | 0.85 | 0.867 | 0.853 | 0.784 | 67.7-89.1 | < 0.001b |
miRNA-511 | < 2.063 | 0.714 | 0.6 | 0.833 | 0.429 | 0.684 | 0.654 | 53.1-77.7 | 0.01a |
miRNA-424 | > 2.462 | 0.829 | 0.48 | 0.817 | 0.5 | 0.737 | 0.559 | 40.4-71.5 | 0.4 |
PPV: Positive predictive value; NPV: Negative predictive value; AUC: Area under curve; 95%CI: 95%Confidence interval.
P value < 0.05 is significant.
P value < 0.01 is highly significant.