Table 6.
Studied miRNA associations with response to treatment according to modified response evaluation criteria in solid tumors
Response to treatment mRECIST
|
Stationary, n = 4 (5.7%)
|
Partial response, n = 7 (10.0%)
|
Complete response, n = 34 (48.6%)
|
Progressive disease, n = 6 (8.6%)
|
P
value
|
miRNA-326 | 11.5 (2.1- 142.6) | 31.1 (6.9- 209.4) | 27.4 (10.0- 155.2) | 69.6 (17.7- 197.9) | 0.5 |
miRNA-511 | 3.8 (0.8- 10.5) | 1.2 (0.3- 4.2) | 1.0 (0.2- 1.5) | 0.6 (0.1- 1.3) | 0.05a |
miRNA-424 | 4.9 (3.0- 8.6) | 4.8 (2.1- 5.1) | 5.4 (2.6- 13.1) | 4.6 (3.1- 15.2) | 0.8 |
mRECIST: Modified Response Evaluation Criteria in Solid Tumors.
P value < 0.05 is significant.