Table 3.
Prognostic predictive value of GRACE score when combined with other indexes.
| ROC analysis | NRI | IDI | ||||
|---|---|---|---|---|---|---|
| AUC (95% CI) | P-value | Estimation (95% CI) | P-value | Estimation (95% CI) | P-value | |
| GRACE score | 0.798 (0.736–0.859) | Reference | Reference | Reference | ||
| +HbA1C | 0.798 (0.734–0.862) | 0.959 | 0.212 (−0.061–0.485) | 0.127 | 0.011 (−0.003–0.024) | 0.123 |
| +FBG | 0.810 (0.748–0.872) | 0.257 | 0.364 (−0.001–0.103) | 0.010 | 0.016 (−0.001–0.033) | 0.070 |
| +TG | 0.841 (0.789 – 0.894) | 0.060 | 0.591 (0.322–0.861) | <0.001 | 0.052 (0.021–0.083) | 0.001 |
| +LDL–C | 0.808 (0.747–0.868) | 0.254 | 0.259 (−0.017–0.536) | 0.066 | 0.007 (−0.004–0.018) | 0.216 |
| +TyG index | 0.849 (0.791–0.907) | 0.043 | 0.718 (0.466–0.971) | <0.001 | 0.086 (0.050–0.122) | <0.001 |
GRACE score, Global Registry of Acute Coronary Events score; TyG index, triglyceride-glucose index; FBG, fasting blood glucose; HbA1c, glycosylated hemoglobin A1c; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; IDI, integrated discrimination improvement; NRI, net reclassification improvement; CI, confidence interval.