Table 1.

Characteristics of included studies: psoriasis and comorbidities.

Study	Region	Study period	Data sources	Mean age, (y); Female (%)		N° of psoriatic patients		N° of Control		Specific comorbidities	NOS
				Psoriasis	Control	All	Comorbidities	All	Comorbidities
Ahlehoff O, 201130	Danish	2002–2006	The Danish National Patient Register	69.5 (12.1); 36.58	70.6 (13.5); 38.72	462	199	48935	20356	CVD, KD, PD	6
Ahlehoff O, 201231	Danish	1997.01–2006.12	The Danish National Patient Register	46.1 ± 16.9; 49.72	43.7 ± 19.7; 49.03	39558	530	4478926	55660	CVD, KD, CD, PD	7
Armstrong AW, 201332	US	2004–2009	University of California Davis	53 (40‒63); 59.19	53 (40‒63); 51.11	2078	1776	6234	3616	CVD, CD, PD	6
Charlton R, 201833	UK	1998.01–2014.12	The UK Clinical Practice Research Datalink	49 (39‒59); 50.95	49 (39‒59); 50.95	27132	8444	27132	7051	CVD, CD	7
Chiang CH, 201134	Taiwan	Before 2007	Longitudinal Health Insurance Database 2007	45.3 ± 17.4; 43.69	43.5 ± 17.4; 22.14	2783	1066	13910	5145	CVD, KD	6
Feldman SR, 201535	US	2007.01–2012.03	The OptumHealth Reporting and Insights claims database	47.62; 44.50	47.62; 44.50	5492	881	5492	499	KD, CD, PD, LD	7
Khalid U, 201536	Danish	1997.01–2011.12	The Danish National Patient Register	43.3 (15.8); 51.48	41.9 (19.9); 5 0.71	70665	1292	5036959	105321	CVD, KD, PD	7
aLee S, 201737	US	2010.11–2015.10	The US Department of Defense population	48.1; 51.84	48.1; 51.84	7249	2932	72490	22367	CVD, CD	7
Min C, 201926	Korean	2002‒2013	The Korean National Health Insurance Service-National Sample Cohort	NR; 43.32	NR; 43.32	11071	5187	44284	20298	CVD, CD	7
Prasada S, 202029	US	2000.01–2019.01	The Northwestern Medicine Enterprise Data Warehouse	49.72 (15.95); 51.71	48.60 (16.65); 57.34	5365	1536	19358	5241	CVD, KD	7
Schell C, 201538	German	NR	Eberhard Karls University Tübingen	48.3 ± 15.6; 43.33	49.1 ± 18.6; 60.00	300	158	300	150	CVD, KD, PD, LD	6
Tollefson MM, 201828	US	2004.01–2013.12	Optum Laboratories Data Warehouse	12.0 (4.4); 53.52	12.0 (4.4); 53.52	29957	1200	29957	646	CVD, LD	8
Vena GA, 201039	Italy	2001‒2005	The Health Search/Thales Database	52.5 (16.5); 47.41	52.4 (16.4); 52.59	3516	399	17580	1425	CVD, PD	6
Yang YW, 201127	Taiwan	2006.01–2007.12	Longitudinal Health Insurance Database2000	NR, >18; 32.58	NR, >18; 67.42	1685	1471	5055	3651	CVD, KD, CD, PD, LD	8
Yeung H, 201340	UK	NR	The Health Improvement Network	46 (37‒55); 49.43	46 (36‒55); 52.91	9035	1945	90350	17502	CVD, KD, CD, PD, LD	6

NR, Not Reported; NOS, Newcastle–Ottawa Quality Assessment Scale; CVD, Cardiovascular Disease; CD, Cerebrovascular Disease; KD, Kidney Disease; PD, Pulmonary Disease; LD, Liver Disease; US, United States; UK, United Kingdom.

^aThe data of study included Psoriatic arthritis.³⁷