Table 2.

Forced expiratory volume in one second (FEV1) at MESA Exam 4: unadjusted and adjusted models

	A. Unadjusted model			B. Adjusted model 1			C. Adjusted model 2
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
SSRI	−88.6	−196.2 to 19.0	0.11	−63.0	−128.0 to 2.1	0.06	−66.0	−131.2 to −0.8	0.048*
SNRI							−511	−182.1 to 79.9	0.44
TCA							72.2	−51.5 to 195.9	0.25
Cigarette smoking status
Never-smokers				Ref	Ref	Ref	Ref	Ref	Ref
Former smokers				1.4	−33.7 to 36.6	0.94	1.6	−33.6 to 36.8	0.93
Current smokers				−116.0	−172.8 to −59.3	<.0001*	−115.9	−172.7 to −59.1	<.0001*
Smoking pack-years				−3.8	−4.6 to −3.0	<.0001*	−3.8	−4.6 to −3.0	<.0001*
CES-D Score				−1.8	−3.7 to 0.04	0.06	−1.8	−3.7 to 0.04	0.06

CES-D: Center for Epidemiological Studies-Depression, SNRI: serotonin-norepinephrine reuptake inhibitors, SSRI: selective serotonin reuptake inhibitors, TCA: tricyclic antidepressants. Shaded variables or values were not included in the model. Beta shows the mean difference. Adjusted model 1: cigarette smoking status (Never, former, and current smokers), smoking pack years, CES-D score, age, sex, race/ethnicity, height and weight. Adjusted model 2: model 1 + serotonin and norepinephrine reuptake inhibitors and tricyclic antidepressants