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The female mice carrying the homologous mutation of Timm8a1-I23fs49X exhibited less gain of weight. (A) Mice at the age of 4–5 weeks [from left to right: wild-type (WT) male, MUT male, WT female, MUT female mouse]. (B) Weekly bodyweight. The Timm8a1 MUT mice were significantly smaller than the WT mice since the 3rd week (****p < 0.0001).
