Table 1:
Baseline characteristics of patients within the different groups.
| Controls | IA | IA CLAD | Asp | Asp CLAD | Total | |
|---|---|---|---|---|---|---|
| N | 9 | 10 | 9 | 10 | 7 | 45 |
| Sex | ||||||
| Female | 2 | 4 | 5 | 4 | 4 | 19 |
| Male | 7 | 6 | 4 | 6 | 3 | 26 |
| Type of transplant | ||||||
| Double lung | 7 | 8 | 8 | 9 | 7 | 39 |
| Single lung | 2 | 2 | 1 | 1 | 0 | 6 |
| Underlying disease | ||||||
| Pulmonary fibrosis | 3 | 2 | 1 | 1 | 1 | 8 |
| COPD | 1 | 4 | 4 | 3 | 2 | 14 |
| Cystic fibrosis | 0 | 1 | 1 | 1 | 1 | 4 |
| Interstitial Lung Disease | 3 | 1 | 0 | 3 | 1 | 8 |
| Others | 2 | 2 | 3 | 2 | 2 | 11 |
| CLAD | 0 | 0 | 9 | 0 | 7 | 16 |
| BAL fungal culture | ||||||
| Aspergillus fumigatus | 0 | 5 | 5 | 3 | 2 | 15 |
| Aspergillus niger | 0 | 0 | 0 | 0 | 3 | 3 |
| Aspergillus flavus | 0 | 0 | 1 | 3 | 1 | 5 |
| Aspergillus versicolor | 0 | 0 | 0 | 0 | 1 | 1 |
| Other | 0 | 0 | 2 | 4 | 0 | 6 |
| No growth | 9 | 0 | 1 | 0 | 0 | 10 |
| Number of patients on immunosuppressive drugs | ||||||
| Tacrolimus | 2 | 2 | 4 | 2 | 3 | |
| Cyclosporine | 8 | 8 | 6 | 8 | 3 | |
| Mycophenolate mofetil | 6 | 8 | 8 | 5 | 5 | |
| Azathioprine | 1 | 1 | 2 | 2 | 1 | |
| Prednisone | 6 | 8 | 8 | 5 | 5 | |
| Median time (days) from transplant to colonization | n/a | 97 | 193 | 238 | 272 | |
| Median time (days) from transplant to CLAD | n/a | n/a | 614 | n/a | 914 |