3. Summary of trials comparing community‐based interventions using rapid diagnostic tests with health facility‐based care.

Study ID	Design	Country (setting)	People trained	Duration of training	Summary of intervention	Summary of control	Outcomes assessed	Drugs/mRDTs free to participants	Supervision
Ohnmar 2012	cRCT	Myanmar (rural)	Unpaid volunteers	2 days	Trained to treat P falciparum malaria after positive mRDT with AL or presumptive P vivax with CQ in those testing negative	Health facility care	Mortality, hospitalizations	Drugs: unclear mRDTs: no	Midwives in nearest health facility routinely monitored/supervised volunteers during their monthly immunization visits. Malaria supervisors also occasionally visited volunteers.
Swana 2016	CBA	Democratic Republic of the Congo (rural)	CHWs	3 days	Trained to treat P falciparum malaria after positive mRDT with AQAS or rectal AS, and to refer if negative mRDT as appropriate	Health facility care	Parasitaemia	Drugs: yes mRDTs: not reported	Initial observation of mRDTs by supervisors with corrective actions over 2–4 days, weekly visits thereafter, 3 monthly meetings with investigators
Thiam 2012	CBA	Senegal (rural)	Home care providers	3 days theory, 2 weeks practical	Trained to treat P falciparum malaria after positive mRDT with AQAS, and to refer if negative mRDT	Health facility care	Mortality, hospitalizations, referrals	Drugs: no (USD 0.6 adults, USD 0.3 children until May 2010) mRDTs: yes	Post‐training follow‐up, monthly supervision by health post head nurse, co‐ordinating meetings by district health teams and nurses in peripheral health facilities

AL: artemether‐lumefantrine; AQ: amodiaquine; AS: artesunate; CBA: controlled before‐after study; CHW: community health worker; CQ: chloroquine; cRCT: cluster‐randomized controlled trial; mRDT: malaria rapid diagnostic test; P falciparum: Plasmodium falciparum; P vivax: Plasmodium vivax.