Table 2.
Comparison of CGM-derived metrics between CSII and MDI groups.
| All patients | MDI group | CSII group | P-value | |
|---|---|---|---|---|
| (n = 362) | (n = 301) | (n = 61) | ||
| eHbA1c (%) | 7.4 (6.7, 8.3) | 7.5 (6.8, 8.4) | 6.9 (6.4, 7.7) | <0.001 |
| %TAR (>10.0mmol/L) | 37.6 (21.3, 52.0) | 39.0 (22.5, 54.6) | 24.8 (17.2, 42.1) | <0.001 |
| TAR <25% (%) | 31.8 | 27.9 | 50.8 | <0.001 |
| %TIR (3.9-10mmol/L) | 58.8 (44.9, 73.5) | 57.2 (43.2, 70.6) | 67.2 (56.4, 79.8) | <0.001 |
| TIR ≥ 70% (%) | 22.7 | 18.3 | 44.3 | <0.001 |
| %TBR (<3.9mmol/L) | 2.2 (0.4, 5.6) | 2.2 (0.3, 5.4) | 1.9 (0.5, 7.7) | 0.578 |
| TBR <4% (%) | 63.8 | 63.8 | 63.9 | 0.983 |
| Mean glucose (mmol/L) | 9.2 (7.9, 10.7) | 9.4 (8.0, 11.0) | 8.3 (7.4, 9.6) | <0.001 |
| SD (mmol/L) | 3.3 (2.7, 4.0) | 3.5 (2.8, 4.1) | 2.9 (2.4, 3.6) | 0.001 |
| MAGE (mmol/L) | 6.6 (5.6, 8.9) | 7.3 (5.8, 9.0) | 6.5 (5.2, 8.2) | 0.019 |
| LAGE (mmol/L) | 16.4 (13.8,18.6) | 16.4 (13.8,18.8) | 15.6 (12.4,17.6) | 0.038 |
| CV (%) | 36.7 (30.1, 42.1) | 36.9 (31.0, 42.2) | 34.7 (29.7, 40.6) | 0.200 |
| CV <36% (%) | 46.4 | 44.2 | 57.4 | 0.060 |
| LBGI | 3.1 (1.7, 5.1) | 3.2 (1.7, 5.1) | 2.7 (1.7,5.0) | 0.676 |
| HBGI | 10.3 (7.0, 15.0) | 11.3 (7.4, 15.7) | 7.5 (5.2, 12.1) | <0.001 |
Data are shown as median (IQR) and frequency.
CGM, continuous glucose monitoring; MDI, multiple daily insulin injection; CSII, continuous subcutaneous insulin infusion; eHbA1c, estimated HbA1c; TAR, time above range; TIR, time in range; TBR, time below range; SD, standard deviation of glucose; MAGE, mean amplitude of glucose excursions; LAGE, mean amplitude of glucose excursions; CV, coefficient of variation; LBGI, low blood glucose index; HBGI, high blood glucose index.
P-values for CSII group vs. MDI group.