Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Non-canonical amino acids in RiPP engineering. A: Structure of microcin J25 (MccJ25, sticks) bound to E. coli RNA polymerase (RNAP, space-filling). The precise positioning of MccJ25 within RNAP was enabled by the incorporation of p-bromophenylalanine (pBrF) into MccJ25. The orange mesh shows the anomalous bromine signal from pBrF. Image derived from PDB file 6N60. B: The cyanobactin patellin 2 was engineered with multiple para- substituted phenylalanine analogs.
