Table 2.
Impact of ever WS exposure on baseline lung function and its declinea
| Group | Years | Ever WS exposure | Ever WS exposurea years |
|---|---|---|---|
| All subjects | |||
| FEV1 (ml/s) | − 24.2 (1.0) | − 75.2 (23.7) | − 4.3 (1.9) |
| P value | < 0.0001 | 0.0016 | 0.025 |
| FVC (ml) | − 15.0 (1.2) | − 26.1 (25.2) | − 2.4 (2.4) |
| P value | < 0.0001 | 0.30 | 0.30 |
| FEV1/FVC ratio (%) | − 0.386 (0.019) | − 1.792 (0.430) | − 0.093 (0.038) |
| P value | < 0.0001 | < 0.0001 | 0.015 |
| Age < 55.9 yearb | |||
| FEV1 (ml/s) | − 24.4 (1.5) | − 65.6 (30.7) | − 0.5 (2.8) |
| P value | < 0.0001 | 0.033 | 0.85 |
| FVC (ml) | − 13.5 (1.7) | − 7.3 (33.1) | − 1.6 (3.2) |
| P value | < 0.0001 | 0.82 | 0.62 |
| FEV1/FVC ratio (%) | − 0.379 (0.029) | − 1.666 (0.493) | − 0.014 (0.053) |
| P value | < 0.0001 | 0.0008 | 0.80 |
| Age ≥ 55.9 yearb | |||
| FEV1 (ml/s) | − 24.0 (1.2) | − 76.6 (36.8) | − 8.7 (2.6) |
| P value | < 0.0001 | 0.038 | 0.001 |
| FVC (ml) | − 16.0 (1.6) | − 37.5 (38.7) | − 3.8 (3.5) |
| P value | < 0.0001 | 0.33 | 0.28 |
| FEV1/FVC ratio (%) | − 0.391(0.026) | − 2.013 (0.724) | − 0.196 (0.055) |
| P value | < 0.0001 | 0.0055 | 0.0004 |
WS woodsmoke
aLinear mixed effects model was used to assess the impact of ever WS exposure on lung function decline through including an interaction term between ever WS exposure and time in cohort. We included fixed effects for baseline age, BMI, height, smoking status, and packyears, sex, and ethnicities, and random effects for intercept and time in cohort.
bCohort was stratified based on a median age of 55.9 year