. Author manuscript; available in PMC: 2022 Sep 8.

Published in final edited form as: Clin Infect Dis. 2018 Jan 6;66(2):185–190. doi: 10.1093/cid/cix773

Table 3.

Cost and Proportion of Antibiotic Expenditures According to Class and Year, 2010–2015

Antibiotic Class	2010^a	2011^a	2012^a	2013^a	2014^a	2015^a	P Value^b

Tetracyclines	1.8 (17.2)	1.9 (19.1)	1.7 (20.2)	2.6 (28.4)	2.0 (22.2)	1.7 (19.2)	.4679
Cephalosporins	0.88 (8.3)	0.91 (9.3)	0.95 (11.2)	1.0 (11.4)	1.1 (11.5)	1.1 (12.2)	.0065
Macrolides	0.86 (8.1)	0.91 (9.3)	0.93 (11.0)	0.85 (9.3)	0.88 (9.6)	0.93 (10.7)	.1913
Penicillins	1.9 (17.9)	1.6 (16.5)	1.4 (16.6)	1.3 (14.5)	1.5 (16.4)	1.4 (16.0)	.2283
Aminoglycosides	0.31 (3.0)	0.34 (3.4)	0.38 (4.5)	0.44 (4.8)	0.38 (4.2)	0.31 (3.7)	.3318
Quinolones	2.2 (21.1)	1.5 (15.1)	0.48 (5.7)	0.42 (4.6)	0.27 (3.0)	0.20 (2.3)	.0103
Sulfonamides	0.07 (0.7)	0.07 (0.7)	0.06 (0.7)	0.07 (0.8)	0.10 (1.1)	0.12 (1.4)	.0124
Oxazolidinones	0.69 (6.6)	0.73 (7.5)	0.71 (8.5)	0.73 (8.0)	0.75 (8.2)	0.59 (6.9)	.6749
Miscellaneous	1.8 (17.2)	1.9 (19.2)	1.8 (21.7)	1.7 (18.2)	2.2 (23.9)	2.4 (27.7)	.0008

Results are reported in millions of dollars (percentage); for each percent value, the denominator is the total expenditure in that calendar year.

P value is evaluating the trend in the proportion of expenditures over 5 years.