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. 2022 Aug 25;13:966348. doi: 10.3389/fphar.2022.966348

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Copyright © 2022 Li, Wang, Zhang, Duan, Qian, Yang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of the main active components (protocatechuic acid and nootkatone) on cell viability and apoptosis in H₂O₂-stimulated PC12 cells (A) Effects of protocatechuic acid on cell viability of H₂O₂-stimulated PC12 cells under different concentration (25, 50 and 100 μg/ml) (B) Effects of nootkatone on cell viability of H₂O₂-stimulated PC12 cells under different concentration (20, 40 and 60μg/ml) (C) Apoptotic assay by flow cytometry (D) Apoptosis ratio statistics. The values were represented as the mean ± SD (n = 3). **p < 0.01 vs model group.