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. Author manuscript; available in PMC: 2022 Sep 8.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2018 Nov 26;110(1):172–187. doi: 10.1016/j.ijrobp.2018.11.028

Table 2.

Variations in RILT grading and lung definitions among 24 recent publications




RILT grading criteria Lung definition for analysis T arget exclusion



CTCAE only 17 Whole (bilateral) lungs 16 GTV 7
CTCAE & SWOG 2 Bilateral lungs and ipsilateral lung 2 IGTV 1
CTCAE & RTOG 1 Ipsilateral lung 2 CTV 2
RTOG 2 NCS 3 ITV 1
SWOG 1 NS 1 PTV 3

NS 1 None or NS 10


RILT=Radiation-Induced Lung Toxicity

NS=Not Specified

NCS=Not Clearly Specified (but can infer bilateral from text)

GTV=Gross Tumor Volume

IGTV=Internal Gross Tumor Volume

ITV=Internal Target Volume

CTV=Clinical Target Volume

PTV=Planning Target Volume