aa |
amino acid; |
aAPC |
artificial antigen-presenting cell; |
AAV |
adeno-associated virus |
ACT |
adoptive cell therapy; |
ADCC |
antibody-dependent cell-mediated cytotoxicity; |
AICD |
activation-induced cell death; |
ALL |
acute lymphoblastic leukemia; |
BBB |
blood-brain barrier; |
CAR |
chimeric antigen receptor; |
CAR-NK |
CAR-modified NK cells; |
CHL |
classical Hodgkin’s lymphoma; |
CLL |
chronic lymphocytic leukemia; |
CRS |
cytokine release syndrome; |
CTL |
cytotoxic T lymphocytes; |
DLBCL |
diffuse large B-cell lymphoma; |
DLL1 |
Delta-like-1; |
EBs |
embryoid bodies; |
EGFR |
epidermal growth factor receptor; |
ES |
embryonic stem cells; |
FasL |
Fas ligand; |
GM-CSF |
granulocyte macrophage colony stimulating factor; |
GMP |
good manufacturing practice; |
GvHD |
graft-versus-host disease; |
HLA-I |
human leukocyte antigen-I; |
HSC |
hematopoietic stem cells; |
ICANS |
immune effector cell-associated neurotoxicity syndrome; |
IFN-γ |
interferon-γ; |
IL |
interleukin; |
iPSCs |
induced pluripotent stem cells; |
ITAM |
immunoreceptor tyrosine-based activation motif; |
KIRs |
killer cell immunoglobulin-like receptors; |
KLRs |
killer lectin-like receptors; |
LILRs |
leukocyte immunoglobulin-like receptors; |
mbIL-21 |
membrane-bound IL-21; |
MDSC |
myeloid-derived suppresive cell; |
MNC |
mononuclear cell; |
NHL |
non-Hodgkin’s lymphoma; |
PB |
peripheral blood; |
PBMCS |
peripheral blood mononuclear cells; |
PB-NKs |
peripheral blood-derived NK cells; |
PD-1 |
programmed cell death protein 1; |
scFv |
single-chain fragment variable; |
sgp130 |
soluble glycoprotein130; |
sIL-2Rα |
soluble interleukin 2 receptor-α; |
TAA |
tumor-associated antigen; |
TAM |
tumor-associated macrophage; |
TCM |
central memory T cell; |
TCRs |
T cell receptors; |
TEM |
effector memory T cells; |
Th1 |
T helper 1; |
TM |
transmembrane domain; |
TME |
tumor microenvironment; |
TN |
naive T cells; |
TNF-α |
tumor necrosis factor-α; |
TRAIL |
TNF-related apoptosis-inducing ligand; |
TRAILR |
TRAIL receptor; |
Treg |
regulatory T cells; |
UCB |
umbilical cord blood; |
UCB-NKs |
Umbilical cord blood-derived NK cells |