AML |
Acute Myeloid Leukemia. |
FLT3i |
FLT3 inhibitors. |
FLT3mut |
FLT3 mutated. |
FLT3ITD |
FLT3 internal tandem duplication. |
FLT3TKD |
Tyrosine kinase domain mutations |
JM |
Juxtamembrane. |
HSCT |
Allogeneic Hemopoietic Stem Cell Transplantation. |
R/R |
Relapsed/refractory. |
PDGF |
Platelet-derived growth factor. |
OS |
Overall survival. |
EFS |
Event free survival. |
DFS |
Disease free survival. |
CCR |
Composite complete remission. |
Cri |
Complete remission with incomplete hematologic recovery. |
CRp |
Complete remission with incomplete platelet recovery. |
VEGF |
Vascular endothelial growth factor. |
RFS |
Relapse free survival. |
ORR |
Overall Response rate. |
MRD |
Minimal residual disease. |
MRDneg |
Negative minimal residual disease. |
MRDpos |
Positive minimal residual disease. |
GVHD |
Graft-versus-host disease. |
FL |
FLT3 ligand. |
VAF |
Variant allel frequency. |
CCT |
Conventional chemotherapy. |
LIT |
Low intensity therapy. |
PCR |
Polymerase chain reaction. |
WES |
Whole exome sequencing. |
CR |
Complete remission. |
FGF2 |
Fibroblast growth factor 2. |
CRISPR-Cas9 |
Unbiased genome-wide clustered regularly interspaced short palindromic repeats. |
GLS |
Glutaminase. |
Rac1 |
Ras-related C3 botulinum toxin substrate 1. |
LSCs |
Leukemic stem cells. |
OME |
Omacetaxine mepesuccinate. |
BID |
Bis in die. |
HMA |
Hypomethylating agents. |