Table 1.

Baseline and tumor characteristics.

	PCN-PDAC n = 233	PDAC n = 1761	p-Value
Baseline characteristics
Male, n(%)	116 (50)	923 (52)	0.45
Age in years, mean (SD)	67 (9.5)	68 (8.8)	0.024
WHO performance status, n (%) a			0.46
0–1	215 (92)	1599 (91)
2–4	18 (8)	162 (9)
(Neo)adjuvant therapy, n (%)			0.08 b
Chemotherapy	128 (55)	1068 (61)
(Chemo)radiotherapy	-	16 (0.9)
Tumor characteristics
pT-stage, n (%) c,d			<0.001
T1	34 (15)	60 (3)
T2	80 (34)	485 (27)
T3	117 (50)	1151 (65)
T4	2 (0.9)	65 (2)
pN-stage, n (%) c,e			<0.001
N0	100 (43)	475 (27)
N1	111 (48)	1098 (62)
N2	22 (9)	188 (11)
R0 resection, n (%) f	120 (52)	748 (42)	0.009
Vascular invasion, n (%) g	102 (44)	1082 (61)	<0.001
Perineural invasion, n (%) h	164 (73)	1523 (86)	<0.001

Percentages might not sum to 100% because of rounding. ^a WHO status was missing for 1156 (58%) of the patients in the original dataset. ^b Fisher’s exact test was used. ^c Depending on the time of registration, tumor and lymph node staging were based on either the seventh or eighth edition of the pathological tumor-node-metastasis (TNM) classification of malignant tumors. ^d T-stage was missing for 116 (5.8%) of the patients in the original dataset. ^e N-stage was missing for 12 (0.6%) of the patients in the original dataset. ^f Radical resection was missing in 5 (0.3%) of the patients in the original dataset. R0-2 was defined according to the International Collaboration on Cancer Reporting. ^g Vascular invasion was missing for 438 patients (22%) in the original dataset. ^h Perineural invasion was missing for 250 patients (13%) in the original dataset. Abbreviations: n = number. PCN = pancreatic cystic neoplasms. PDAC = pancreatic ductal adenocarcinoma. pT = tumor stage. pN = nodal stage. SD = standard deviation. WHO = World Health Organization. Bold means significant difference.