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. 2022 Sep 1;11(17):2733. doi: 10.3390/cells11172733

Figure 3.

Figure 3

Gene expression of the examined genes of the PCR arrays of ASC, MCF-7 cells and corresponding co-cultures. (A) From left to right, ASC, MCF-7 cells and co-culture were each treated with 5 µg, 15 µg or 25 µM tamoxifen for 48 or 96 h. The color coding (see Figure 2) indicates a relative increase (black) or reduction (red) in gene expression. The 84 genes studied and their associated pathways in tumorigenesis and transformation are listed in Table 1. (B) ASC of passage 2 after treatment with 25 µM tamoxifen after 96 h in culture. (C) MCF-7 cells of passage 32 after treatment with 25 µM tamoxifen after 96 h in culture. (D) Co-culture of ASC and MCF-7 cells after treatment with 25 µM tamoxifen after 96 h in culture.