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. 2022 Aug 25;14(17):4106. doi: 10.3390/cancers14174106

Table 3.

Association of metabolic syndrome or its components with the risk of thyroid cancer in female participants.

Characteristics Number of Subjects Number of Subjects with Thyroid Cancer Incidence Per 10,000 Person-Years RR (95% CI) * p Value
Metabolic syndrome <0.001
No 1,790,507 29,095 19.6 Reference
Yes 398,970 7062 21.3 1.16 (1.13–1.19)
Metabolic syndrome components
Abdominal obesity <0.001
No 1,837,100 2,9855 19.6 Reference
Yes 352,377 6302 21.5 1.15 (1.12–1.18)
Elevated blood pressure <0.001
No 1,201,990 19,146 19.2 Reference
Yes 987,487 17,011 20.7 1.17 (1.15–1.20)
Hyperglycaemia 0.008
No 1,622,855 26,832 19.8 Reference
Yes 566,622 9325 19.9 1.03 (1.01–1.06)
Hypertriglyceridemia <0.001
No 1,733,640 28,499 19.8 Reference
Yes 455,837 7658 20.2 1.06 (1.04–1.091)
Low HDL-cholesterol <0.001
No 1,615,362 25,599 19.1 Reference
Yes 574,115 10,558 22.1 1.19 (1.16–1.22)

RR, relative risk; CI, confidence interval; HDL, high-density lipoprotein. * Adjusted for age and body mass index.