Table 4.
Univariable and multivariable binary logistic regression analysis for grade 3 or higher radiation pneumonitis.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Sex (Male) | 7.606 (1.002–57.709) | 0.054 | ||
| Age (>70) | 1.400 (0.498–3.934) | 0.523 | ||
| ECOG PS (2 or higher) | 3.054 (1.231–7.580) | 0.016 | 3.162 (1.215–8.226) | 0.018 |
| Smoking History (Yes) | 2.349 (0.669–8.252) | 0.183 | ||
| COPD (Yes) | 1.444 (0.633–3.297) | 0.383 | ||
| ILD (Yes) | 2.479 (0.886–6.937) | 0.084 | ||
| T stage (T2) | 1.731 (0.635–4.718) | 0.284 | ||
| Operability (Inoperable) | 8.846 (1.165–67.144) | 0.035 | 7.204 (0.929–55.863) | 0.059 |
| Baseline FEV1 (<40%) | 3.818 (1.062–13.731) | 0.040 | ||
| Baseline DLCO (<40%) | 4.980 (1.636–15.162) | 0.005 | 3.995 (1.259–12.675) | 0.019 |
| Respiratory motion control (No) | 0.611 (0.162–2.310) | 0.468 | ||
| Treatment modality (Photon) | 0.631 (0.233–1.710) | 0.365 | ||
OR, odds ratio; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; COPD, chronic obstructive pulmonary disease; ILD, interstitial lung disease; FEV1, forced expiratory volume in 1 s; DLCO, diffusion capacity of lung for carbon monoxide.