Table 12.

Patient characteristics indicative of stereotypically HPV-driven oropharyngeal, oral cavity, and laryngeal SCC that may be the basis for the precise selection of patients for whom treatment de-escalation is possible.

Characteristic
HR HPV Positive
Oropharyngeal sub-site
$\mathrm{Younger} \mathrm{age} \mathrm{or} \le 50$
Never- or ex-smoker