Table 1.
HCC-related snoRNAs.
| snoRNA | Chromosomal Location | Host Gene | Role in HCC | Expression | Sample Size, HCC/Control | Targets | Reference |
|---|---|---|---|---|---|---|---|
| SNORD52 | 6p21.33 | SNHG32 | Oncogene | Up | 80/80 | CDK1 | [56] |
| SNORD17 | 20p11.23 | SNX5 | Oncogene | Up | 175/175 | NPM1, MYBBP1A |
[28] |
| SNORD126 | 14q11.2 | CCNB1IP-1 | Oncogene | Up | 30/30 | hnRNPK | [55,57] |
| SNORA42 | 1q22 | KHDC4 | Oncogene | Up | 60/60 | P53, p21 | [58] |
| ACA11 | 4p16.3 | NSD2 | Oncogene | Up | 92/92 | - | [46] |
| SNORD105 | 19p13.2 | PPAN-P2Rγ11 | Oncogene | Up | 712/801 | PPAN | [59] |
| SNORD72 | 5p13.1 | - | Oncogene | Up | 46/46 | ID2 | [60] |
| SNORD76 | 1q25.1 | GAS5 | Oncogene | Up | 66/66 | Fibronectin, vimentin | [47] |
| snoU2_19 | 4, 7 | - | Oncogene | Up | 80/80 | β-catenin | [33] |
| SNORA47 | 5q13.3 | ZBED3 | Oncogene | Up | 60/60 | - | [61] |
| SNORA24 | 4q26 | SNHG8 | Tumor suppressor | Down | 91/91 | 18S rRNA | [54] |
| SNORD50A SNORD50B |
6q14.3 | SNHG5 | Tumor suppressor | Down | - | K-Ras | [62] |
| SNORD113-1 | 14q32.31 | MEG8 | Tumor suppressor | Down | 112/112 | ERK1/2, SMAD2/3 | [63] |
| SNORA23 | 11p15.4 | IP07 | Tumor suppressor | Down | - | 28S rRNA | [64] |
The expression of snoRNA with sample size information was verified in HCC and normal liver tissues.