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Rates of KRAS mutations in NSCLC and subtypes.
| Cancer | Mutation Rates | |||
|---|---|---|---|---|
| KRAS | KRAS Exon 2 Mutations Rate | KRAS Exon 3 Mutations Rate | KRAS Exon 4 Rate Considering the Total of KRAS Mutations | |
| NSCLC | 25–30% | 34% | 1.89% | 0.24% |
| Lung AC | 30–35% | 27% | 7% | <1% |
| SCC | 3–4% | 7% | <3% | <0.5% |
AC: AdenoCarcinoma; NSCLC: Non-Small Cell Lung Cancer; SCC: Squamous-Cell Carcinoma (AACR Project GENIE Consortium, 2017 [7]).
