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. 2022 Aug 27;11(17):2662. doi: 10.3390/cells11172662

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The reduced serum concentration of purine catabolites and improved total plasma antioxidant status (TAOS) in R6/1 mice treated with rosiglitazone. Serum uric acid (A), hypoxanthine (B), inosine (C) concentration, and total plasma antioxidant status (D) in R6/1 (HD) and R6/1 with rosiglitazone treated mice (HD + Rosiglitazone). Data presented as mean ± SEM, n = 5–6, * p < 0.05, *** p < 0.001. The red dotted lines present the mean value of the investigated parameter in control, C57BL/6J mice (adapted from supplementary materials and our previous work [30]).