Figure 3.
Female A-KO mice have reduced weight gain and fat mass following HFD-feeding. (A) Growth curves of female WT and A-KO mice fed a HFD (n = 11–15). (B) Cumulative locomotor activity over a 24 h period (n = 8). (C) Cumulative food consumption over a 24 h period (n = 7). (D) Fat mass and lean mass measured by whole body composition nuclear magnetic resonance (n = 11–16). (E) Tissue weight measurements of SQ, VF and liver at time of sacrifice (n = 10–15). (F) Hepatic triglyceride measured per gram liver (n = 10–16). Data represent mean ± SEM. * p < 0.05, ** p < 0.01, ns, not significant. SQ, subcutaneous adipose tissue; VF, visceral adipose tissue.
