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. 2022 Aug 25;13:945709. doi: 10.3389/fpsyg.2022.945709

TABLE 5.

Results of analyses between musical activity and GMV at the voxel level.

No. cluster Label (Hammersmith atlas) Brodmann area (BA) Hemisphere Cluster Peak of cluster


P size Z value MNI coordinates
(x y z)
Main effect: musical activitya
1 Postcentral gyrus BA 6 Left 0.195 220 3.60 –57 –6 27
Interaction effectb
1 Precentral gyrus BA 6 Left 0.025 718 4.90 –28 –10 48
2 Precentral gyrus BA 4 Left 0.114 322 4.81 –39 –14 33
3 Inferior middle temporal gyrus BA 20 Right 0.054 502 4.45 51 –12 –42
4 Fusiform gyrus BA 20 Left 0.279 145 3.99 –36 –8 –38
5 Inferior frontal gyrus BA 46 Lateral/right 0.140 277 3.90 40 33 12
6 Anterior medial temporal lobe BA 38 Left 0.245 168 3.78 –38 16 –36
7 Orbito-frontal lobe BA 11 Medial/right 0.166 242 3.59 6 34 –14
8 Postcentral gyrus BA 4 Right 0.293 137 3.52 50 –8 26

Models adjusted for scanner site and TIV.

Musical activity was included as binary predictor, dummy coded with musical activity = 1, no musical activity = 0.

aResults from the main effect model with musical activity and GMV (p < 0.001 uncorrected, expected voxels per cluster k = 140).

bResults from the interaction effect model with musical activity, working memory, and GMV (p < 0.001 uncorrected, expected voxels per cluster k = 134).

Significant after FWE correction (p < 0.05, expected voxels per cluster k = 42).

Cluster peaks are specified by their anatomical site, labeled using the Hammersmith atlas provided by the CAT12 toolbox.

Brodmann areas were identified with the BioImage Suite Web 1.2.0.GMV, gray matter volume; MNI coordinates (x y z), coordinates in MNI space in millimeters; TIV, total intracranial volume.