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. 2022 Aug 26;14(17):4122. doi: 10.3390/cancers14174122

Table 1.

Summary of breast cancer risk reduction categories considered.

Risk Factor Evidence from National Cancer Institute (NCI) [21] Recommendations for Breast Cancer Prevention Evidence from American Institute for Cancer Research Continuous Update Project Findings [8] Number (#) of High-Quality a, Multilevel EBCCPs in a Population Facing Breast Cancer Disparities b/# of EBCCPs Meeting the Quality Criteria/# of NCI EBCCPs
Physical Activity Decreases risk Strong evidence of decreased pre and postmenopausal risk. 2/10/41
Higher Body Fatness in
Young Adulthood
Not discussed Probable evidence of decreased pre and postmenopausal risk. 1/4/16
Adult Body Fatness (marked by BMI, waist circumference, and waist-hip ratio) and Weight Gain in Adulthood Increases risk Strong evidence of increased postmenopausal breast cancer risk. 0/1/13
Alcohol Increases risk Strong evidence that alcohol increases pre and postmenopausal breast cancer, no strong evidence for other dietary factors. 0
Tobacco Exposure in Early Life Not discussed Not discussed in report. 0/13/16
Breastfeeding Reduces risk Probable evidence of decreased pre and postmenopausal risk. 0
Environmental Chemical Exposures Not clear Not discussed. 0

a High-quality was defined as receiving an independent score of ≥3 for research integrity, intervention impact, and dissemination capability; and receiving an independent score of ≥50% for reach, effectiveness, adoption, and implementation. b Health disparities population defined as a multiracial/multiethnic population with ≤50% non-Hispanic White, a socioeconomically disadvantaged group, and/or a medically underserved or rural geographic area.