Table 1.
Risk Factor | Evidence from National Cancer Institute (NCI) [21] Recommendations for Breast Cancer Prevention | Evidence from American Institute for Cancer Research Continuous Update Project Findings [8] | Number (#) of High-Quality a, Multilevel EBCCPs in a Population Facing Breast Cancer Disparities b/# of EBCCPs Meeting the Quality Criteria/# of NCI EBCCPs |
---|---|---|---|
Physical Activity | Decreases risk | Strong evidence of decreased pre and postmenopausal risk. | 2/10/41 |
Higher Body Fatness in Young Adulthood |
Not discussed | Probable evidence of decreased pre and postmenopausal risk. | 1/4/16 |
Adult Body Fatness (marked by BMI, waist circumference, and waist-hip ratio) and Weight Gain in Adulthood | Increases risk | Strong evidence of increased postmenopausal breast cancer risk. | 0/1/13 |
Alcohol | Increases risk | Strong evidence that alcohol increases pre and postmenopausal breast cancer, no strong evidence for other dietary factors. | 0 |
Tobacco Exposure in Early Life | Not discussed | Not discussed in report. | 0/13/16 |
Breastfeeding | Reduces risk | Probable evidence of decreased pre and postmenopausal risk. | 0 |
Environmental Chemical Exposures | Not clear | Not discussed. | 0 |
a High-quality was defined as receiving an independent score of ≥3 for research integrity, intervention impact, and dissemination capability; and receiving an independent score of ≥50% for reach, effectiveness, adoption, and implementation. b Health disparities population defined as a multiracial/multiethnic population with ≤50% non-Hispanic White, a socioeconomically disadvantaged group, and/or a medically underserved or rural geographic area.