Figure 3.

Plasma levels of IGF-2 (ng/mL) and IGFBP-7 (ng/mL) in SZ patients. (a) Levels of IGF-2 are significantly downregulated in the FE group when compared against both ME_A and ME_T; (b) Levels of IGFBP-7 are significantly downregulated in the FE group when compared against both ME_A and ME_T. Tukey’s multiple comparison test was applied, and significant p-values are shown in each graph. FE: First Episode drug-naïve patients, ME: multiple or chronic patients, ME_A: ME who had abandoned treatment at least 1 month before the psychotic episode took place, and ME_T: ME who had been following treatment until the psychotic episode took place.