Table II.
Univariate risk factors for recurrence: characteristics of surgery
| Surgery characteristics | Recurrence in BCC |
Recurrence in SCC |
||||
|---|---|---|---|---|---|---|
| No n = 4,248 (%) | Yes n = 154 (%) | p-value | No n = 330 (%) | Yes n = 41 (%) | p-value | |
| Time from pre-surgical consultation to surgery, months, median (IQR) | 1.5 (0.9–2.6) | 1.6 (1–2.6) | 0.5187 | 1.1 (0.5–2.2) | 0.7 (0.4–1.7) | 0.1934 |
| Time in operating room, min*, median (IQR) | 75 (60–100) | 90 (60–120) | 0.0212 | 80 (55–110) | 90 (60–122) | 0.0324 |
| Defect difference (major axis – minor axis in mm), median (IQR) | 4 (1–8) | 5 (2–10) | 0.0179 | 5 (0–10) | 10 (5–20) | 0.0030 |
| Hospitalization, n (%) | 689 (17) | 39 (27) | 0.0017 | 94 (30) | 15 (44) | 0.1035 |
| Mohs surgery types, n (%) | 0.5458 | 0.079 | ||||
| Fresh-tissue technique | 4,025 (95) | 143 (93) | NA | 237 (72) | 24 (59) | NA |
| Slow Mohs | 220 (5) | 10 (7) | NA | 93 (28) | 17 (41) | NA |
| Number of stages, n (%) | 0.0002 | 0.0002 | ||||
| 1 | 2,407 (57) | 62 (41) | NA | 204 (62) | 15 (37) | NA |
| 2 | 1,360 (32) | 63 (41) | NA | 104 (32) | 17 (41) | NA |
| 3 or more | 458 (11) | 27 (18) | NA | 20 (6) | 9 (22) | NA |
| Number of blocks, n (%) | 0.3206 | 0.2745 | ||||
| 1 | 391 (10) | 8 (6) | NA | 35 (11) | 2 (5) | NA |
| 2 | 1,115 (28) | 34 (27) | NA | 62 (20) | 5 (14) | NA |
| 3 or more | 2,464 (62) | 86 (67) | NA | 211 (69) | 30 (81) | NA |
| Unfinished surgery | 56 (1) | 11 (7) | 0.0000 | 11 (3) | 7 (17) | 0.0001 |
| Extent level, n (%) | 0.0128 | 0.0048 | ||||
| Epidermis | 26 (1) | 4 (3) | NA | 10 (3) | 2 (5) | NA |
| Dermis | 2,049 (50) | 63 (43) | NA | 106 (33) | 9 (22) | NA |
| Hypodermis | 1,678 (41) | 61 (41) | NA | 138 (44) | 11 (27) | NA |
| Fascia | 108 (3) | 6 (4) | NA | 15 (5) | 6 (15) | NA |
| Muscle | 242 (6) | 11 (7) | NA | 39 (12) | 11 (27) | NA |
| Bone | 27 (1) | 3 (2) | NA | 9 (3) | 2 (5) | NA |
| Specialist who repaired, n (%) | 0.8831 | 0.7324 | ||||
| Dermatologist | 4,149 (98) | 148 (98) | 316 (96) | 41 (100) | ||
| Plastic surgeon | 36 (1) | 1 (1) | 3 (1) | 0 (0) | ||
| Other | 45 (1) | 2 (1) | 11 (3) | 0 (0) | ||
| Reconstruction technique, n (%) | 0.0294 | 0.1140 | ||||
| Healing by secondary intention | 484 (11) | 17 (11) | NA | 68 (21) | 10 (24) | NA |
| Direct closure | 1,128 (27) | 42 (27) | NA | 87 (26) | 10 (24) | NA |
| Flap | 1,993 (47) | 58 (38) | NA | 103 (31) | 10 (24) | NA |
| Graft | 498 (12) | 31 (20) | NA | 62 (19) | 6 (15) | NA |
| Complete closure | 142 (3) | 5 (3) | NA | 10 (3) | 5 (12) | NA |
| Dermatologist participates in the interpretation, n (%) | 3,129 (74) | 91 (59) | 0.0001 | 202 (61) | 21 (51) | 0.2091 |
| Pathologist participates in the interpretation, n (%) | 3,221 (76) | 140 (92) | 0.0000 | 296 (90) | 38 (93) | 0.5804 |
| Intra or post-surgical morbidity, n (%) | 277 (7) | 16 (11) | 0.0478 | 26 (8) | 6 (15) | 0.1535 |
*
Time waiting outside operating room was excluded.
BCC: basal cell carcinoma; SCC: squamous cell carcinoma; NA: non-applicable; IQR: interquartile range. Bold p-values indicate statistically significant results.