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. 2021 Nov 10;101(11):369. doi: 10.2340/actadv.v101.369

Table II.

Changes in atopic dermatitis-associated parameters after 16 weeks dupilumab treatment following adjustment for clinical findings

Characteristics Coefficient 95% CI p-value
Total Eczema Area and Severity Index
Week –1.25 –1.39, –1.10 < 0.001
Clinical findings
 General type Reference
 Facial type 5.34 1.02, 9.66 0.015
 Prurigo type 5.04 –1.56, 11.63 0.134
Head and Neck Eczema Area and Severity Index
Week –0.12 –0.14, –0.11 < 0.001
Clinical findings
 General type Reference
 Facial type 0.62 0.12, 1.11 0.015
 Prurigo type –0.73 –1.51, 0.05 0.066
Patient-Oriented Eczema Measure
Week –0.74 –0.82, –0.65 < 0.001
Clinical findings
 General type Reference
 Facial type 1.09 –0.90, 3.07 0.283
 Prurigo type 0.01 –2.99, 3.00 0.996
Itch Numerical Rating Scale
Week –0.26 –0.30, –0.22 < 0.001
Clinical findings
 General type Reference
 Facial type –0.32 –1.06, 0.42 0.401
 Prurigo type 0.06 –1.04, 1.16 0.915

95% CI: 95% confidence interval.