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FAK-degrading efficiency of PROTACs A1–A15 in A549 cells (A) FAK levels in response to dose escalations of A1–A15 in the A549 cell line after treatment for 12 h, with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) used as the loading control. The experiments were repeated three times, and representative images were selected. (B) FAK protein expression ratio vs control.
