Table 3.
The membrane permeability of PROTAC A13 in Caco-2 cell lines.
| Compd. | A–B permeability (Papp × 10-6 cm/s)a | B-A permeability (Papp × 10-6 cm/s)a | Efflux ratio (Papp(B−A)/ Papp(A−B)) |
|---|---|---|---|
| B5 | <0.480 | 0.417 | >0.869 |
aDuplicates were performed (n = 2).
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