Table 1.
Main components of cold storage solutions (CSSs) and machine perfusion solutions (MPSs). CSS: cold storage solution; HES: hydroxyethyl starch; HTK: histidine–tryptophan–ketoglutarate; IRI: ischemia/reperfusion injury; K+: potassium intracellular ion; MPS: University of Wisconsin (Belzer) machine perfusion solution; Na+: sodium extracellular ion; PEG: polyethylene glycol; UW: University of Wisconsin (Belzer).
| Component/Function | Cold Storage Solutions (CSSs) | Machine Perfusion Solutions (MPSs) | |||
|---|---|---|---|---|---|
| HTK | UW CSSs | Celsior | IGL-1 | UW MPSs | |
| Osmotic | Manitol/Ketoglutarate | Raffinose/Lactobionate | Manitol/Lactobionate | Raffinose/Lactobionate | Glucose/Gluconate/Ribose |
| Buffer | Histidine | PO4 | Histidine | PO4 | PO4/HEPES |
| Oncotic | − | HES | − | PEG | HES |
| Na+ | Low | Low | High | High | High |
| K+ | Low | High | Low | Low | Low |
| Antioxidant/IRI Protection | Tryptophan | Adenosine/ Glutathione/Allopurinol | Glutathione | Adenosine/Glutathione/ Allopurinol | Glutathione/Adenine |