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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Nano Res. 2021 Oct 12;15(3):2300–2314. doi: 10.1007/s12274-021-3813-1

Figure 3.

Figure 3

PBNP-PTT + aCD137 improves the survival of metachronous tumor-bearing mice through abscopal effect. (a) Schematic overview of the study. Two SM1 tumors were inoculated into opposite sides of C57BL/6 mice four days apart. Secondary tumors were left untreated. Tumor growth observed in mice treated with (b) CTRL, (c) aCD137, (d) PBNP-PTT, and (e) PBNP-PTT + aCD137, with (f) tumor growth curves superimposed for comparison. Each line represents an individual mouse; solid lines represent the primary tumors and dashed lines represent the secondary tumors. (g) Survival of tumor-bearing animals post-treatment. n = 4–5/group; *p < 0.05, **p < 0.01 compared with CTRL and aCD137.