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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Nano Res. 2021 Oct 12;15(3):2300–2314. doi: 10.1007/s12274-021-3813-1

Figure 5.

Figure 5

PBNP-PTT + aCD137 enhances DC activation in lymph nodes and generates systemic T cell activation and memory. Synchronous SM1 tumors were established and treated as described. Lymph nodes were harvested and analyzed for (a) CD11c, (b) CD80, and (c) CD86 expression. Spleens were harvested and analyzed for (d)–(f) CD4, (g)–(i) CD8, ((e) and (h)) CD25, ((f) and (i)) CD69, and ((j)–(m)) CD62 and CD44 expression levels. Values represent means ± SD, n = 5/group; ns: not significant, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.