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. Author manuscript; available in PMC: 2022 Sep 8.
Published in final edited form as: ACS Biomater Sci Eng. 2017 Apr 18;3(11):2889–2899. doi: 10.1021/acsbiomaterials.6b00688

Figure 1 |.

Figure 1 |

a) SELP sequences are composed of alternating silk-like (GAGAGS) and elastin-like (GXGVP) blocks, where X represents the interchangeable residue responsible for modulating the transition temperature. In this study we consider the sequence [(GVGVP)4(GYGVP)(GVGVP)3(GAGAGS)]14. b) UV Spectrophotometry heating and cooling curves show a reversible transition range between 28–45°C. c) SELP samples at i) low (7°C) and ii) high (57°C) temperature. d) Representative SELP structures from simulation, at i) 7°C and ii) 57°C. Dotted lines represent end-to-end molecular distance. e) End-to-end distance of representative SELP structures pictures in d) at 7°C and 57°C. f) Hydrodynamic radius from dynamic light scattering of SELP at 7°C and 57°C. g) SELP hydrogel samples at i) 7°C and ii) 57°C.