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. 2022 Sep 1;11(17):2654. doi: 10.3390/foods11172654

Table 1.

Advantages and disadvantages of different extraction methods.

Extraction Method Advantages Disadvantages
Hot water/alkali extraction Optimal rheological properties and purity of the extracted hydrocolloids Involves high temperatures and very long extraction time
Long extraction time and high temperature may affect extracted compounds’ functionalities
Use of hazardous chemical solvents
High cost of chemical solvents
Microwave-assisted extraction (MAE) Use of water instead of chemical solvents High temperature can deteriorate thermolabile compounds
It provides locally heat raw materials, enhanced biomass digestion, reduced process time, solvent consumption, and costs
Extracted compounds possess good quality
It utilizes directly on fresh biomass from seaweed
Ultrasound-assisted extraction (UAE) Ability to achieve larger yield of extracts utilizing water High noise levels involved (safety issues)
Ultrasound might bring to depolymerization of compounds
It increases extraction yield with lower extraction time Due to the high cost of energy and equipment, UAE needs a large amount of capital to get started on an industrial scale
Efficient, environmentally friendly, and low extraction processes. Low equipment expenses and maintenance, possibility to scale-up to industrial production, reduced number of process steps UEA applications are still limited
Extraction techniques used in food industry
Ability to obtain larger yield of extracts utilizing aqueous-based solvent High-pressure involved (safety issue)
Pressurized solvent extraction (PSE) High-pressure power can bring depolymerization of compounds
It has high extraction performance, less solvent usage, quick extraction time, and does not imply the use of hazardous solvents These processes might degrade labile compounds due to high temperature and pressure
Scarcity of application on seaweed extractions
Enzyme-assisted extraction (EAE) Ability to achieve larger yield of compounds utilizing water Scarcity of application on seaweed extractions
It is inexpensive, highly efficient, possibility to scale up, avoid the use of any harmful chemicals or organic solvents and it has shorter extraction time
It preserves the structural integrity of the target compounds extracted that exert important bioactivities suitable for cosmetic, nutraceutical and pharmaceutical industries