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. 2022 Aug 24;23(17):9583. doi: 10.3390/ijms23179583

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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GLP-1 receptor activation induces an anti-inflammatory response. Abbreviatures: NFκB: Nuclear Factor kappa B; IKKK: IκB kinase kinase; IKKβ: IκB kinase β; pro-IL-1β: pro-interleukin-1β; pro-IL-18: pro-interleukin-18; ASC: Apoptosis-associated Speck-like protein containing a CARD; NEK7: NIMA Related Kinase 7; AMPK: adenosine monophosphate-activated protein kinase; SIRT1: Sirtuin 1; GSMD: Gasdermin D; IL-1β: interleukin-1β; IL-2: interleukin-2; IL-6: interleukin-6; MCP1: Monocyte chemoattractant protein 1; ICAM: Intracellular adhesion molecule-1; VCAM: Vascular cell adhesion molecule-1; NAD/NADH: Nicotinamide adenine dinucleotide. Partially Biorender. com used.