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. 2022 Aug 24;23(17):9573. doi: 10.3390/ijms23179573

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Representative photomicrographs of the rat skin tissues in the control, drug-free chitosan-coated naringenin and chitosan-coated naringenin (CNNE) treated groups of abrasion model in albino Wistar rats. (A) Wound area before the treatment at day 0, (B) control group at day 14, (C) drug-free chitosan-coated naringenin formulation treated group at day 14, and (D) CNNE treated group at day 14. (I: inflammatory cells; B: blood vessels; K: keratinization; Star icon: granulated tissue). Reproduced with permission from Akrawi et al., “Development and Optimization of Naringenin-Loaded Chitosan-Coated Nanoemulsion for Topical Therapy in Wound Healing”, published by MDPI, 2020 [72].