Table 1.

Compounds with anti-inflammation.

Compound	Origin	Using Part	Other Bioactivities	Targeting Phase	ExperimentalModel	Type of Wound	Ref.
Asiatic acid	Plant (Centella asiatica)	Leaves	Anti-microbial Anti-oxidant Pro-collagen	Inflammation Proliferation Remodeling	Human	Diabetic Burn	[174]
Pinocembrin	Plant	N/A	N/A	Inflammation	HaCaT cell	N/A	[113]
Ursolic acid	Plant (Hedyotis herbacea)	N/A	Anti-microbial	Inflammation	Rat	Incision Excision	[175]
Myricetin	Plant (Tecomaria capensis v. aurea)	N/A	Anti-oxidant Anti-allergic Analgesic	Inflammation	Rat	Excision	[47]
Myricetin	Plant	N/A	Anti-oxidant	N/A	In vitro	N/A	[59]
Apigenin	Plant	Fruits Beans Tea leaves	Anti-oxidant Pro-angiogenic	Inflammation Proliferation	Rat	Random skin flaps	[109]
Lupeol	Plant (Bowdichia virgilioides Kunth)	Stem bark	Anti-oxidant	Inflammation Proliferation Remodeling	Rat	Excision	[58]
Lupeol	Plant (Bowdichia virgilioides Kunth)	Stem bark	Anti-oxidant	Inflammation Proliferation	Rat	Excision	[176]
Steroidal glycoside	Plant	N/A	Dermal fibroblast migration activity	Inflammation Proliferation Remodeling	Human dermal fibroblast cells	Human wound	[56]
Verbascoside	Plant (Plantago subulata)	Aerial parts	Anti-oxidant Anti-fugal Anti-bacterial Anti-viral	Inflammation Proliferation	L929 fibroblasts RAW 264.7 cells	N/A	[62]
Verbascoside	Plant (Plantago australis)	Leaves	Anti-oxidant Healing	Inflammation Proliferation	HaCaT cells Rat	Excision	[177]
Hesperetin	Plant	Citrus species	Anti-microbial Anti-oxidant	Inflammation Proliferation Remodeling	Rat	Excision diabetic foot ulcer	[102]
Hesperetin	Plant	Citrus species	Anti-oxidant Pro-collagen	Inflammation	Rat	Diabetic foot ulcer	[154]
Carophylolide	Plant (Calophyllum inophyllum Linn)	Seed	Anti-microbial Anti-coagulant	Inflammation	Mice	Incision	[55]
Artocarpin	Plant (A.communis.)	Heartwood	Anti-oxidative, Anti-microbial	Inflammation Proliferation	Mice HUVECs cells	Excision	[50]
Bilirubin	Mammals	Product of heme catabolism	Anti-oxidant	Inflammation Proliferation Remodeling	Rat	Excision	[138]