Table 3.
Compound | Origin | Using Part | Other Bioactivities | Target Phase | Experimental Model | Type of Wound | Ref. |
---|---|---|---|---|---|---|---|
Chitosan | Animal (Crab) |
Shells | Anti-microbial Anti-inflammation |
Inflammation | Diabetic db/db mice | Excision wound | [222] |
Pinocembrin | Animal (Bee) |
PropolisHoney | Anti-oxidation Anti-inflammatory Anti-apoptosis |
Proliferation | Human Keloid fibroblast Mice |
keloid xenograft | [103] |
Lupeol | Plant (Bowdichia virgilioides Kunth) |
Stem bark | Anti-oxidant Antidiabetic |
Inflammation Proliferation Remodeling |
Rat | Excision | [58] |
Hydrogen peroxide | Animal (Bee) |
Honey | N/A | Inflammation | HaCaT cells | N/A | [223] |
Methylglyoxal | Animal (Bee) |
Honey (Manuka) | N/A | N/A | N/A | N/A | [52] |
Tannins | Plant (E. phaseoloides (L.) Merr) |
N/A | Anti-oxidant Anti-inflammatory |
Inflammation Proliferation Remodeling |
Rat | Excision | [105] |
Arnebin-1 | Plant (Arnebianobilis) |
Root | Anti-fungal | Proliferation | Rat | Excision | [147] |
Hydroalcoholic extract | Plant (Caseariasylvestris Sw.) |
Leaves | Anti-inflammatory Antiseptic |
Proliferation | Rodent | Scald burns | [83] |
Dichloromethane andhexanoic fractions | Plant (Calendula officinalis L.) |
Flower | Anti-inflammatory Anti-septic |
Inflammation Proliferation | Rat | Excision | [129] |
Lawsone | Plant (Lawsonia Alba Lam.) |
Leaves | Anti-fungal Anti-parasitic Anti-viral |
N/A | Rat | Excision Incision |
[111] |