Table 4.
Prevalence of antimicrobial non-susceptible isolates pre- and post-PCV13 in Cambodia for multidrug resistance (non-susceptible for three or more antimicrobials), penicillin (using the resistance threshold for meningitis), erythromycin, chloramphenicol, tetracycline, co-trimoxazole and specific genes including cat (chloramphenicol) and tet (tetracycline), as well as macrolide resistance genes mef and ermB
|
Antimicrobial/gene |
pre-PCV (N=258) |
post-PCV13 (N=428) |
Total (N=686) |
|---|---|---|---|
|
Multidrug resistance |
204 (79.1 %) |
325 (75.9 %) |
529 (77.1 %) |
|
Penicillin (meningitis threshold) |
210 (81.4 %) |
355 (82.9 %) |
565 (82.4 %) |
|
Erythromycin |
142 (55.0 %) |
211 (49.3 %) |
353 (51.5 %) |
|
Chloramphenicol |
30 (11.6 %) |
61 (14.3 %) |
91 (13.3 %) |
|
Tetracycline |
231 (89.5 %) |
392 (91.6 %) |
623 (90.8 %) |
|
Co-trimoxazole |
228 (88.4 %) |
346 (80.8 %) |
574 (83.7 %) |
|
mef presence |
61 (23.6 %) |
82 (19.2 %) |
143 (20.8 %) |
|
ermB presence |
107 (41.5 %) |
155 (36.2 %) |
262 (38.2 %) |
|
cat presence |
30 (11.6 %) |
61 (14.3 %) |
91 (13.3 %) |
|
tet presence |
226 (87.6 %) |
383 (89.5 %) |
609 (88.8 %) |