Table 5.
Relationship between AMR and VT serotypes for five different antimicrobials and macrolide-resistance genes
Adjusting for multiple testing (threshold 0.005), all except tet are significantly associated with VT serotypes. Antimicrobials and genes: penicillin (using the resistance threshold for meningitis), erythromycin, tetracycline, chloramphenicol, co-trimoxazole and specific genes including cat (chloramphenicol) and tet (tetracycline), as well as the macrolide-resistance genes mef and ermB.
|
Antibiotic/gene |
Odds ratio [95 % confidence intervals] |
P value |
|---|---|---|
|
Multidrug resistance |
6.46 [4.09–10.5] |
<0.01 |
|
Penicillin |
6.39 [3.79–11.24] |
<0.01 |
|
Erythromycin |
6.76 [4.76–9.68] |
<0.01 |
|
Tetracycline |
2.65 [1.46–4.98] |
<0.01 |
|
Chloramphenicol |
3.56 [2.12–6.17] |
<0.01 |
|
Co-trimoxazole |
6.55 [3.8–11.86] |
<0.01 |
|
ermB |
3.55 [2.52–5.02] |
<0.01 |
|
mefA |
9.11 [5.44–15.96] |
<0.01 |
|
cat |
3.56 [2.12–6.17] |
<0.01 |
|
tet |
2.07 [1.23–3.56] |
0.0050 |