Fig. 2.
Statistical data of viral circRNAs. (a) Pie chart showing the distribution of cancers included in this analysis. The subgraph of the pie chart shows the subtypes of lymphoma. (b) The number of viral circRNAs identified from five viruses, MERS-CoV, KSHV, EBV, rLCV and HPV18. (c) The distribution of the number of junction reads for detecting viral circRNAs from each sample. (d) The distribution of circRNA expression measured by the natural logarithm of CPM. (e) The distribution of viral circRNA length. (f) The number of circRNAs identified across the samples. Graphical representation of EBV (g), KSHV (h), MERS-CoV (i) and rLCV (j) circRNAs using the program circlize. The outer circle of the viral genome is arranged in clockwise order, with each arch connecting the starting position and ending position of a single circRNA in the inner circle. The gradient colour of the arches corresponds to the expression level of circRNAs, characterized by the natural logarithm of the average CPM for each circRNA. Both positive- (red) and negative- (blue) strand circRNAs are shown. The purple curve and blue curve in the middle circle indicate the number of viral circRNAs for which each nucleotide is covered on the plus strand and minus strand, respectively.
